Operative Techniques in Orthopaedics
Volume 18, Issue 2 , Pages 86-94 , April 2008

Biomechanical Strategies for Managing Atrophic and Oligotrophic Nonunions

  • Ivan S. Tarkin, MD

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Ivan S. Tarkin, MD, Department of Orthopaedic Surgery, Division of Orthopaedic Trauma, University of Pittsburgh Medical Center, Kaufmann Medical Building, 3471 Fifth Avenue, Suite 911, Pittsburgh, PA 15213
    • ,
  • John M. Sojka, MD

References 

  1. Ring D, Perey BH, Jupiter JB. The functional outcome of operative treatment of ununited fractures of the humeral diaphysis in older patients. J Bone Joint Surg Am. 1999;81:177–190
  2. Kloen P, Doty SB, Gordon E, et al. Expression and activation of the BMP-signaling components in human fracture nonunions. J Bone Joint Surg Am. 2002;84-A:1909–1918
  3. Tarkin IS, Cole PA. Pilon fractures. In:  DiGiovanni C,  Greisberg J editor. Core Knowledge in Orthopaedics: Foot and Ankle. St. Louis: Elsevier; 2007;p. 252–266
  4. Brinker MR, O'Connor DP, Monla YT, et al. Metabolic and endocrine abnormalities in patients with nonunions. J Orthop Trauma. 2007;21:557–570
  5. Johnson EE, Urist MR, Finerman GA. Distal metaphyseal tibial nonunion (Deformity and bone loss treated by open reduction, internal fixation, and human bone morphogenetic protein (hBMP)). Clin Orthop Relat Res. 1990;250:234–240
  6. Bhattacharyya T, Bouchard KA, Phadke A, et al. The accuracy of computed tomography for the diagnosis of tibial nonunion. J Bone Joint Surg Am. 2006;88:692–697
  7. Chapman M, Finkemeier GC. Treatment of supracondylar nonunions of the femur with plate fixation and bone graft. J Bone Joint Surg Am. 1999;81:1217–1228
  8. Hohl JB, Plakseychuk A, Kobbe P, et al: Correction of complex lower extremity deformities: Is it worth the effort? 23rd Annual Meeting of the Orthopedic Trauma Association, Boston (MA), October 17-20, 2007
  9. Zelle BA, Gruen GS, Klatt B, et al. Exchange reamed nailing for aseptic nonunion of the tibia. J Trauma. 2004;57:1053–1059
  10. Reed LK, Mormino MA. Functional outcome after blade plate reconstruction of distal tibia metaphyseal nonunions: A study of 11 cases. J Orthop Trauma. 2004;18:81–86
  11. Zelle B, Gruen G, Espiritu M, et al. Posterior blade plate fusion: A salvage procedure in severe posttraumatic osteoarthritis of the tibiotalar joint. Op Tech Orthop. 2003;16:68–75
  12. Ring D, Kloen P, Kadzielski J, et al. Locking compression plates for osteoporotic nonunions of the diaphyseal humerus. Clin Orthop Relat Res. 2004;425:50–54
  13. Nadkarni B, Srivastav S, Mittal V, et al. Use of locking compression plates for long bone nonunions without removing existing intramedullary nail: review of literature and our experience. J Trauma. 2008;65:482–486
  14. Ueng SWN, Cha EN, Lee SS, et al. Augmentative plate for the management of femoral nonunion after intramedullary nailing. J Trauma. 1997;43:640–644
  15. Sama D, Toro JB, Peterson M, et al. Plate fixation of ununited humeral shaft fractures: Effect of type of bone graft on healing. J Bone Joint Surg Am. 2006;88:1442–1447
  16. Ahlmann E, Patzakis M, Roidis N, et al. Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes. J Bone Joint Surg Am. 2002;84-A:716–720
  17. Kobbe P, Tarkin IS, Pape HC. Use of the ‘reamer irrigator aspirator’ system for non-infected tibial non-union after failed iliac crest grafting. Injury. 2008;39:796–800
  18. Kobbe P, Tarkin IS, Pape HC, et al. Voluminous bone graft harvesting of the femoral marrow cavity for autologous transplantation: An indication for the “Reamer-Irrigator-Aspirator-” (RIA-) technique (in German). Unfallchirurg. 2008;111:469–472
  19. Quintero AJ, Ivan S, Tarkin IS, et al: Unexpected events with the reamer-irrigator-aspirator device when harvesting autologous bone. 24th Annual Meeting of the Orthopedic Trauma Association, Denver (CO), October 15-18, 2008
  20. Friedlaender GE, Perry CR, Cole JD, et al. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. J Bone Joint Surg Am. 2001;83-A(suppl):151–158
  21. Govender S, Csimma C, Genant HK, et al. Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: A prospective, controlled, randomized study of four hundred and fifty patients. J Bone Joint Surg Am. 2002;84:2123–2134

PII: S1048-6666(08)00037-2

doi: 10.1053/j.oto.2008.10.003

Operative Techniques in Orthopaedics
Volume 18, Issue 2 , Pages 86-94 , April 2008

Article Tools

* Image Usage & Resolution